CompaniesRanked

2874 companies · fiscal year 2025 · SEC EDGAR · September 25, 2026

Companies that spend the most on research and development — page 5

Ranks 401–500 of 1270 · Fiscal year 2025 · Data as of September 25, 2026

R&D expense
#CompanyR&D expenseYoY15-year trend
401Clearwater AnalyticsCWANUSTechnology$196M+30.3%
402PeoplePPLIUSTechnology$196M−14.1%
403GrailGRALUSHealthcare$196M−39.3%
404WatersWATUSTechnology$196M+6.9%
405JfrogFROGUSTechnology$195M+21.3%
406Altria GroupMOUSConsumer staples$195M−6.3%
407Tandem Diabetes CareTNDMUSHealthcare$193M−2.9%
408DuPont de NemoursDDUSMaterials$193M−4.9%
409Rapid7RPDUSTechnology$191M+10.1%
410AppfolioAPPFUSTechnology$190M+18.7%
411CalixCALXUSCommunication services$190M+5.8%
412Harmony BiosciencesHRMYUSHealthcare$190M+30.0%
413Enphase EnergyENPHUSTechnology$189M−6.1%
414Fair IsaacFICOUSTechnology$188M+9.5%
415Lattice SemiconductorLSCCUSTechnology$188M+18.0%
416RambusRMBSUSTechnology$188M+15.2%
417QiagenQGENNLHealthcare$188M−3.1%
418Leidos HoldingsLDOSUSTechnology$187M+24.7%
419QuidelorthoQDELUSHealthcare$186M−14.9%
420Mirum PharmaceuticalsMIRMUSHealthcare$186M+32.4%
421Amneal PharmaceuticalsAMRXUSHealthcare$186M−2.4%
422Bloom EnergyBEUSIndustrials$186M+25.1%
423LivanovaLIVNGBHealthcare$186M+1.8%
424UpworkUPWKUSTechnology$186M−11.3%
425InterdigitalIDCCUSFinancials$185M−7.6%
426AlvotechALVOLUHealthcare$184M+7.5%
427Axsome TherapeuticsAXSMUSHealthcare$183M−2.0%
428Zoominfo TechnologiesGTMUSTechnology$182M−7.2%
429Ribbon CommunicationsRBBNUSTechnology$179M−0.6%
430Fresenius Medical CareFMSDEHealthcare$179M−10.1%
431Doubleverify HoldingsDVUSTechnology$178M+16.6%
432MSCIMSCIUSTechnology$178M+11.9%
433Lantheus HoldingsLNTHUSHealthcare$177M+5.5%
434Nebius GroupNBISNLTechnology$177M+54.4%
435VontierVNTUSTechnology$176M−1.1%
436Allison TransmissionALSNUSConsumer discretionary$174M−13.0%
437OshkoshOSKUSConsumer discretionary$174M+2.7%
438SchrodingerSDGRUSHealthcare$173M−14.2%
439Tempus AiTEMUSTechnology$173M+15.8%
440Cooper CompaniesCOOUSHealthcare$172M+11.0%
441AppianAPPNUSTechnology$172M+5.4%
442Telix PharmaceuticalsTLXAUHealthcare$171M+33.9%
443Lotus TechnologyLOTCNConsumer discretionary$171M−37.8%
444UbiquitiUIUSTechnology$170M+6.2%
445BrunswickBCUSIndustrials$169M−0.5%
446Rhythm PharmaceuticalsRYTMUSHealthcare$167M−29.7%
447BrazeBRZEUSTechnology$167M+24.8%
448Kraft HeinzKHCUSConsumer staples$167M+11.3%
449Resideo TechnologiesREZIUSIndustrials$167M+50.5%
450Amkor TechnologyAMKRUSTechnology$167M+2.3%
451Biocryst PharmaceuticalsBCRXUSHealthcare$166M−4.9%
452NewmontNEMUSMaterials$166M−15.7%
453DoverDOVUSIndustrials$165M+10.5%
454RalliantRALUSTechnology$165M+0.9%
455ViasatVSATUSCommunication services$165M+15.8%
456FreshworksFRSHUSTechnology$163M−0.8%
457Jack Henry & AssociatesJKHYUSTechnology$163M+9.8%
458FastlyFSLYUSTechnology$163M+17.9%
459ToroTTCUSIndustrials$162M−6.2%
460Commvault SystemsCVLTUSTechnology$162M+10.9%
461DiodesDIODUSTechnology$162M+21.0%
462Digitalocean HoldingsDOCNUSTechnology$162M+13.4%
463CSG Systems InternationalCSGSUSTechnology$162M+2.1%
464Himax TechnologiesHIMXCNTechnology$161M+0.5%
465TG TherapeuticsTGTXUSHealthcare$160M+69.9%
466Netscout SystemsNTCTUSTechnology$159M+4.3%
467Harley-DavidsonHOGUSConsumer discretionary$159M+0.4%
468Estee Lauder CompaniesELUSConsumer staples$158M+7.6%
469Payoneer GlobalPAYOUSTechnology$155M+15.4%
470NCR VoyixVYXUSTechnology$155M−1.3%
471Q2 HoldingsQTWOUSTechnology$154M+7.7%
472Indie SemiconductorINDIUSTechnology$154M−12.0%
473Prairie OperatingPROPUSEnergy$153M+302.4%
474Five9FIVNUSTechnology$152M−8.3%
475AutohomeATHMCNTechnology$152M−15.8%
476Otis WorldwideOTISUSTechnology$152M0.0%
477Etoro GroupETORILFinancials$151M+15.4%
478NavanNAVNUSTechnology$151M+23.6%
479LearLEAUSConsumer discretionary$151M−1.5%
480GlaukosGKOSUSHealthcare$151M+10.4%
481Owens CorningOCUSMaterials$150M+14.5%
482Dentsply SironaXRAYUSHealthcare$150M−9.1%
483Kulicke & Soffa IndustriesKLICSGTechnology$150M−1.1%
484HUTCHMED (China)HCMHKHealthcare$148M−30.1%
485Liveramp HoldingsRAMPUSTechnology$148M−16.1%
486Taboola.comTBLAUSTechnology$148M+3.9%
487WoodwardWWDUSIndustrials$148M+4.9%
488Globus MedicalGMEDUSHealthcare$147M−10.1%
489MacrogenicsMGNXUSHealthcare$147M−16.9%
490LindeLINGBMaterials$147M−2.0%
491DauchDCHUSConsumer discretionary$147M−7.5%
492Universal DisplayOLEDUSTechnology$146M−7.1%
493Church & DwightCHDUSConsumer staples$146M+4.2%
494Manhattan AssociatesMANHUSTechnology$145M+5.4%
495Acm ResearchACMRUSIndustrials$145M+37.5%
496TeleflexTFXUSHealthcare$145M+32.8%
497NovaNVMIILTechnology$143M+30.1%
498Monte Rosa TherapeuticsGLUEUSHealthcare$142M+16.4%
499Acuity Inc. (De)AYIUSTechnology$140M+37.0%
500Chargepoint HoldingsCHPTUSTechnology$139M−1.4%

All figures from SEC filings · FY2025 · 100

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