Companies in the United States that spend the most on R&D — page 5

Ranks 401–500 of 1030 · Fiscal year 2025 · Data as of September 25, 2026

R&D expense
#CompanyR&D expenseYoY15-year trend
401HappenHAPNUSFinancials$139M−17.4%
402CognexCGNXUSTechnology$139M−0.6%
403CargurusCARGUSTechnology$138M−0.5%
404BlackbaudBLKBUSTechnology$138M−10.1%
405Stoke TherapeuticsSTOKUSHealthcare$138M+54.7%
406IntappINTAUSTechnology$138M+21.2%
407Hyster-YaleHYUSIndustrials$137M+1.0%
408Avery DennisonAVYUSMaterials$137M−0.9%
409Lyondellbasell IndustriesLYBUSMaterials$136M+0.7%
410AnaptysbioANABUSHealthcare$136M−17.0%
411Nextdoor HoldingsNXDRUSTechnology$135M+5.7%
412XperiXPERUSTechnology$135M−29.4%
413BandwidthBANDUSTechnology$133M+11.7%
414NewmarketNEUUSMaterials$132M+5.8%
415AllegionALLEUSIndustrials$132M+17.1%
416Onto InnovationONTOUSTechnology$132M+15.9%
417DoximityDOCSUSTechnology$131M+40.5%
418Keros TherapeuticsKROSUSHealthcare$130M−25.3%
419Leonardo DRSDRSUSIndustrials$129M+40.2%
420BeldenBDCUSMaterials$129M+14.6%
421Life360LIFUSTechnology$128M+13.6%
422AerovironmentAVAVUSIndustrials$128M+26.8%
423NcinoNCNOUSTechnology$128M−1.5%
424PagerdutyPDUSTechnology$127M−10.3%
425GoproGPROUSConsumer discretionary$127M−31.8%
426Tyson FoodsTSNUSConsumer staples$126M+18.9%
427Karyopharm TherapeuticsKPTIUSHealthcare$126M−12.3%
428CelaneseCEUSMaterials$125M−3.8%
429ZiprecruiterZIPUSTechnology$125M−7.6%
430Opko HealthOPKUSHealthcare$124M+17.9%
431CotyCOTYUSConsumer staples$123M−3.0%
432Vishay IntertechnologyVSHUSTechnology$122M+1.9%
433CourseraCOURUSTechnology$122M−7.9%
434PhreesiaPHRUSTechnology$121M+3.5%
435Goodrx HoldingsGDRXUSTechnology$121M−2.2%
436CloroxCLXUSConsumer staples$121M−4.0%
437HeicoHEIUSIndustrials$121M+8.7%
438NextpowerNXTUSTechnology$121M+52.3%
439EnovisENOVUSHealthcare$120M+31.8%
440HuntsmanHUNUSMaterials$120M−0.8%
441Veeco InstrumentsVECOUSIndustrials$120M−3.9%
442SitimeSITMUSTechnology$119M+11.3%
443Alkami TechnologyALKTUSTechnology$118M+23.1%
444TransDigm GroupTDGUSIndustrials$118M+10.3%
445Ipg PhotonicsIPGPUSTechnology$117M+6.9%
446Pacira BiosciencesPCRXUSHealthcare$117M+43.8%
447QualysQLYSUSTechnology$117M+4.9%
448Zeta GlobalZETAUSTechnology$117M+29.2%
449JBT MarelJBTMUSIndustrials$116M+456.5%
450FormfactorFORMUSTechnology$116M−5.1%
451Ingersoll RandIRUSIndustrials$114M−2.0%
452Newell BrandsNWLUSMaterials$114M−7.3%
453Envista HoldingsNVSTUSHealthcare$114M+15.0%
4548x8EGHTUSTechnology$113M−8.3%
455IttITTUSIndustrials$111M−4.7%
456Vanda PharmaceuticalsVNDAUSHealthcare$109M+46.8%
457BlacklineBLUSTechnology$109M+8.1%
458Johnson & JohnsonJNJUSHealthcare$109M−94.1%
459Axcelis TechnologiesACLSUSIndustrials$109M+3.3%
460ChemoursCCUSMaterials$108M−0.9%
461Weatherford InternationalWFRDUSEnergy$108M−12.2%
462LittelfuseLFUSUSIndustrials$107M−0.8%
463Myriad GeneticsMYGNUSHealthcare$107M−5.8%
464Planet Labs PBCPLUSTechnology$107M+5.7%
465Supernus PharmaceuticalsSUPNUSHealthcare$106M−2.4%
466McCormickMKCUSConsumer staples$106M+3.1%
467AptargroupATRUSMaterials$105M+9.4%
468DanaDANUSConsumer discretionary$105M−42.9%
469PhiniaPHINUSConsumer discretionary$105M−6.3%
470VerisignVRSNUSTechnology$104M+7.1%
471Lennox InternationalLIIUSIndustrials$103M+10.5%
472Inspire Medical SystemsINSPUSHealthcare$103M−9.6%
473ImpinjPIUSTechnology$103M+3.8%
474First AdvantageFAUSTechnology$102M+59.6%
475Caris Life SciencesCAIUSHealthcare$102M−10.8%
476Sprout SocialSPTUSTechnology$101M−1.5%
477Power IntegrationsPOWIUSTechnology$101M+0.3%
478N-AbleNABLUSTechnology$101M+11.0%
479MillerknollMLKNUSIndustrials$100M+6.9%
480Campbell'sCPBUSConsumer staples$100M−2.0%
481Bio-TechneTECHUSHealthcare$99.5M+2.9%
482AtricureATRCUSHealthcare$99.2M+3.2%
483Integra LifesciencesIARTUSHealthcare$99.0M−14.2%
484Soundhound AiSOUNUSTechnology$98.3M+39.3%
485RPM InternationalRPMUSMaterials$97.9M+3.4%
486CerenceCRNCUSTechnology$97.8M−19.6%
487AmplitudeAMPLUSTechnology$97.6M+0.0%
488Merit Medical SystemsMMSIUSHealthcare$97.4M+11.3%
489Pacific Biosciences of CaliforniaPACBUSTechnology$97.3M−27.9%
490Semrush HoldingsSEMRUSTechnology$97.2M+21.3%
491Solstice Advanced MaterialsSOLSUSMaterials$97.0M+16.9%
492Indivior PharmaceuticalsINDVUSHealthcare$97.0M−9.3%
493AvientAVNTUSMaterials$96.7M−2.0%
494Air Products & ChemicalsAPDUSMaterials$96.3M−3.9%
495SprinklrCXMUSTechnology$96.0M+4.8%
496McKessonMCKUSHealthcare$96.0M+35.2%
497NovantaNOVTUSTechnology$95.5M−0.0%
498Curtiss WrightCWUSIndustrials$95.2M+3.8%
499Ironwood PharmaceuticalsIRWDUSHealthcare$95.1M−14.6%
500Smith A OAOSUSConsumer discretionary$95.0M−6.6%

All figures from SEC filings · FY2025 · 100

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