R&D expense · 2011–2025

Ionis Pharmaceuticals R&D expense

$916M+1.6% · FY2025

Ionis Pharmaceuticals (IONS) reported $916M in R&D expense for fiscal 2025, +1.6% year on year.

$153M2011$155M2012$174M2013$239M2014$320M2015$340M2016$373M2017$412M2018$462M2019$531M2020$638M2021$900M2023$902M2024$916M2025
Ionis Pharmaceuticals — R&D expense, 2011–2025
Fiscal yearR&D expenseChangeFiling
FY20252025-12-31$916M+1.6%Open →
FY20242024-12-31$902M+0.2%Open →
FY20232023-12-31$900M+41.0%Open →
FY20212021-12-31$638M+20.2%Open →
FY20202020-12-31$531M+15.1%Open →
FY20192019-12-31$462M+12.0%Open →
FY20182018-12-31$412M+10.6%Open →
FY20172017-12-31$373M+9.4%Open →
FY20162016-12-31$340M+6.5%Open →
FY20152015-12-31$320M+33.7%Open →
FY20142014-12-31$239M+37.5%Open →
FY20132013-12-31$174M+12.4%Open →
FY20122012-12-31$155M+1.0%Open →
FY20112011-12-31$153M—Open →

R&D expense — Research and development expense is what the company charged to R&D in the income statement for the year. Most companies report no R&D at all — the line is absent rather than zero — so this ranking covers the roughly 40% of filers that do.

Every row links to its own SEC filing · Fiscal year 2025 · Data as of September 25, 2026 · 2011–2025 compound annual growth +13.6%

R&D expense at companies of similar size

Full ranking by R&D expense →

Cite this page

Ready-made references for the figures on this page, as published on September 25, 2026.

Wikipedia

{{cite web |title=Ionis Pharmaceuticals R&D expense |url=https://companiesranked.com/en/company/ionis-pharmaceuticals/research-and-development-expense |website=CompaniesRanked |date=2026-09-25 |language=en}}

APA 7

CompaniesRanked. (September 25, 2026). Ionis Pharmaceuticals R&D expense. CompaniesRanked. https://companiesranked.com/en/company/ionis-pharmaceuticals/research-and-development-expense

BibTeX

@misc{companiesranked-en-company-ionis-pharmaceuticals-research-and-development-expense-2026,
  author       = {{CompaniesRanked}},
  title        = {{Ionis Pharmaceuticals R\&D expense}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/company/ionis-pharmaceuticals/research-and-development-expense}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

The filing itself

The numbers above are read from this document: 10-K · 0000874015-26-000115 · February 26, 2026

{{cite web |title=Ionis Pharmaceuticals R&D expense — 10-K (0000874015-26-000115) |url=https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/form10k.htm |website=SEC EDGAR |publisher=U.S. Securities and Exchange Commission |date=2026-02-26}}

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