Alnylam Pharmaceuticals (ALNY) reported $3.7B in revenue for fiscal 2025, +65.2% year on year. That ranks #973 by revenue among 2853 SEC filers and #85 in Healthcare. Net income was $314M, a net margin of 8.4%. Revenue has grown 62.4% a year on average since 2016 ($47.2M then). The fiscal 2025 balance sheet shows $5.0B in total assets, $1.7B in cash and $676M in long-term debt.

Key figures

$47.2M2016$89.9M2017$74.9M2018$220M2019$493M2020$844M2021$1.0B2022$1.8B2023$2.2B2024$3.7B2025
Alnylam Pharmaceuticals — Key figures
Key figuresFY2025YoYSource
RevenueRevenueFromContractWithCustomerExcludingAssessedTax$3.7B+65.2%FY20252025-12-31
Gross profitNot reported—
Operating incomeOperatingIncomeLoss$502M+$678MFY20252025-12-31
Net incomeNetIncomeLoss$314M+$592MFY20252025-12-31
Operating cash flowNetCashProvidedByUsedInOperatingActivities$524M+$532MFY20252025-12-31
Capital expenditurePaymentsToAcquirePropertyPlantAndEquipment$58.7M+71.2%FY20252025-12-31
Total assetsAssets$5.0B+17.1%FY20252025-12-31
Shareholders' equityStockholdersEquity$789M+1,076.3%FY20252025-12-31
CashCashAndCashEquivalentsAtCarryingValue$1.7B+71.5%FY20252025-12-31
Long-term debtLongTermDebt$676M+253.3%FY20212021-12-31

Revenue is total net sales for the fiscal year, taken from each company's own annual filing.

Reported since the last full year

Three-month figures this company has filed since FY2025. A quarter is not comparable with a full year, and these figures are used nowhere else on the site: not in any ranking, not in comparisons, not in the download.

Alnylam Pharmaceuticals — Reported since the last full year
QuarterRevenueNet incomeSource
Q2 20262026-06-30$1.3B$164MOpen →

Only periods that end on a calendar quarter appear here. A company whose fiscal year ends in June files on a different calendar, so it has no row.

Where this sits in its sector

Each bar is the spread of the whole sector: the box covers the middle half of companies, the line inside it the median, and the triangle this company. The axis is clipped at the 5th and 95th percentile so a single outlier does not flatten it.

Alnylam Pharmaceuticals — Where this sits in its sector
Where this sits in its sectorFY2025Position in sector
Net marginRank 67 of 161 companies compared8.4%
Operating marginRank 59 of 160 companies compared13.5%
R&D as share of revenueRank 11 of 102 companies compared35.5%
Cash as share of revenueRank 12 of 160 companies compared44.6%

All four are ratios derived from two reported lines, not single filing items. Peer group: companies in the same sector with revenue of $1bn or more; loss-making companies are included.

Profile

Legal name
Alnylam Pharmaceuticals, Inc.
Ticker
ALNY
Exchange
Nasdaq
SIC classification
Pharmaceutical Preparations (2834)
Fiscal year end
12-31
CIK
0001178670

Filings

Similar in size, same sector

CompanyRevenueNet income
Charles River Laboratories InternationalCRL$4.0B−$144M
Alignment HealthcareALHC$3.9B−$724,000
GenmabGMAB$3.7B$963M
Alnylam PharmaceuticalsALNY$3.7B$314M
Dentsply SironaXRAY$3.7B−$598M
Acadia HealthcareACHC$3.3B−$1.1B
Surgery PartnersSGRY$3.3B−$77.9M

See the full ranking →

Cite this page

Ready-made references for the figures on this page, as published on September 25, 2026.

Wikipedia

{{cite web |title=Alnylam Pharmaceuticals — Key figures |url=https://companiesranked.com/en/company/alnylam-pharmaceuticals |website=CompaniesRanked |date=2026-09-25 |language=en}}

APA 7

CompaniesRanked. (September 25, 2026). Alnylam Pharmaceuticals — Key figures. CompaniesRanked. https://companiesranked.com/en/company/alnylam-pharmaceuticals

BibTeX

@misc{companiesranked-en-company-alnylam-pharmaceuticals-2026,
  author       = {{CompaniesRanked}},
  title        = {{Alnylam Pharmaceuticals — Key figures}},
  year         = {2026},
  howpublished = {\url{https://companiesranked.com/en/company/alnylam-pharmaceuticals}},
  note         = {Compiled from SEC EDGAR XBRL filings; data as of 2026-09-25},
  urldate      = {2026-09-25}
}

The filing itself

The numbers above are read from this document: 10-K · 0001628280-26-007497 · February 12, 2026

{{cite web |title=Alnylam Pharmaceuticals — Key figures — 10-K (0001628280-26-007497) |url=https://www.sec.gov/Archives/edgar/data/1178670/000162828026007497/alny-20251231.htm |website=SEC EDGAR |publisher=U.S. Securities and Exchange Commission |date=2026-02-12}}

The figures are rebuilt with every data refresh, so the reference carries the publication date. Add your own access date if your style requires one.